Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
亚型
IgG1
免疫原
Purified recombinant human CHD3 (C-terminus) protein fragments expressed in E.coli.
性状
Lyophilized or Liquid
Swiss Prot
Q12873
克隆号
7F6-G2-E5
克隆类型
Monoclonal Antibody
来源
Mouse
背景资料
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.