Anti-CD14 Polyclonal Antibody

英文名称Rabbit CD14 Polyclonal Antibody别名CD14应用WB稀释比例WB:1:3000交叉反应Human蛋白分子量40kDaGene ID929保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.纯化方法Affinity purification亚型unknown免疫原Synthetic Peptide性状Lyophilized or LiquidSwiss ProtP08571克隆类型Polyclonal Antibody来源Rabbit背景资料Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL-?(PubMed:23880187).