产品名:派洛宁Y ,Dye content≥50% 英文名:Pyronin Y CAS号:92-32-0
分子式:C17H19N2OCl
分子量:302.81
MDL号:MFCD00011725
属性
溶解性 Soluble in water (30 mg/mL), methyl cellosolve (9 mg/mL), and ethanol (3 mg/mL).
存贮条件 否
熔点 250-260°C
密度 否
荧光 否
IC50 否
pK Values 否
描述
别名 3,6-双(二甲基氨基)呫吨鎓氯化物;Pyronin G;Pyronin J;3,6-Bis(dimethylamino)xanthylium chloride
产品介绍 Pyronin Y is a dye that intercalates and stains RNA red, and has been shown to accumulate in the mitochondria of viable cells. Multidrug-resistant (MDR) Acinetobacter baumannii studies tested inhibition of the efflux pump by measuring the intracellluar accumulation of Pyronin Y and Ethidium bromide. Research shows that at low Pyronin Y concentrations the cytostatic effect is cell arrest in the G1 phase, whereas at high concentrations the cells arrest is in the G2 and S phase. Pyronin Y has been used in combination with Alcian Blue to asses and study pulmonary diseases, and in combination with Methyl Green to stain nucleic acids in paraffin sections. Additionally Pyronin Y has been used to measure RNA in flow cytometry.
用途 Used in Unna-Pappenheim stain to demonstrate RNA (red) in contrast to DNA (green). Also used for bacteria staining.