产品名:腺苷-3‘,5‘-环状单磷酸钠水合物 ,99% 英文名: Adenosine 3‘,5‘-Cyclic Monophosphate Sodium Sa CAS号:37839-81-9 分子式:C10H11N5NaO6P·xH2O 分子量:351.19(as Anhydrous) Beilstein号: 54612 EC号: MDL号:MFCD00069736 PubChem编号:24891151 属性 敏感性对热敏感 存贮条件存储温度-20°C 密度否 荧光否 IC50否 pK Values否 描述 别名cAMP-Na;环化腺苷酸 钠盐;腺苷-3‘,5‘-环单磷酸 钠盐 水合物;3‘,5‘-Cyclic AMP sodium salt;cAMP-Na;3‘,5‘-Cyclic AMP Sodium Salt Hydrate 产品介绍Adenosine 3‘,5‘-cyclic monophosphate sodium salt is a naturally-occurring activator of PKA (cAMP-dependent protein kinase A). Cyclic-AMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has shown to induce differentiation, inhibit cell proliferation, and lead to apoptosis. Adenosine 3‘,5‘-cyclic monophosphate sodium salt monohydrate is an activator of Epac. 用途Adenosine-3‘,5‘-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle. 生化机理环化腺苷酸依赖性蛋白激酶 (PKA) 的自然活化剂。cAMP 是一种重要的第二信使,并且在很多系统中与神经递质或激素诱导的受体激活相关。已有显示,cAMP/PKA 信号通路可抑制细胞增殖,诱导分化并导致细胞凋亡。