ABS 059-20 is specific for human oxyntomodulin. Cross-reacts fully with glucagon.
Immunogen
Synthetic full length oxyntomodulin coupled to carrier.
Application
ELISA
Species reactivity (positive)
Human, mouse and rat
Species reactivity (negative)
Not determined
Clone number
20
Epitope
ABS 059-20 has a different epitope specificity than ABS 064-46 and ABS 064-23.
Content
Available in 200 µL and 1mL size. 1mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa.