4-8ºC without exposure to light. No precautions necessary during handling.
克隆性:
多克隆
标记物:
见说明书
适应物种:
见说明书
保质期:
12个月
抗原来源:
Human
目录编号:
MON U-6
级别:
见说明书
库存:
大量
供应商:
上海信裕生物科技有限公司
宿主:
Human
应用范围:
ELISA, WB, IHC-F
浓度:
见说明书
靶点:
见说明书
抗体英文名:
Anti-Urokinase plasminogen activator (human, uPA)
抗体名:
Anti-Urokinase plasminogen activator (human, uPA)
规格:
200ug/1mg
Anti-Urokinase plasminogen activator (human, uPA)
Cat. No.
MON U-6
Product name
Anti-Urokinase plasminogen activator (human, uPA)
Description
Mouse monoclonal antibody
Specificity
MON U-6 is specific for human uPA. No reaction with human tissue plasminogen activator (tPA) is seen when tested by ELISA, immunoblotting and enzyme inhibition. No reaction with any other human plasma proteins is seen when tested by immunoblotting. MON U-6 binds single and two-chain uPA, uPA/PAI-1 complex and uPA/uPAR complex. A reaction is seen with the amino terminal fragment (ATF) but not with LMW uPA.
Immunogen
Native human uPA.
Application
ELISA, WB, IHC-F
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass
IgG1
Gene ID
5328
Clone number
U-6
Epitope
MON U-6 binds to the A-chain of uPA
Content
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Urokinase plasminogen activator (uPA) is a serine protease. It converts the abundant proenzyme plasminogen to active plasmin and plays a key role in cancer invasion and a variety of tissue remodelling processes such as wound healing, mammary gland involution and placental development. Elevated levels of uPA are associated with poor prognosis in many types of cancer (1).