4-8ºC without exposure to light. No precautions necessary during handling.
克隆性:
多克隆
标记物:
见说明书
适应物种:
见说明书
保质期:
12个月
抗原来源:
Rat, Human
目录编号:
HYB 131-18
级别:
见说明书
库存:
大量
供应商:
上海信裕生物科技有限公司
宿主:
Rat, Human
应用范围:
ELISA, WB
浓度:
见说明书
靶点:
见说明书
抗体英文名:
Anti-MBL
抗体名:
Anti-MBL (rat, human)
Anti-MBL (rat, human)
Cat. No.
HYB 131-18
Product name
Anti-MBL (rat, human)
Description
Mouse monoclonal antibody
Specificity
HYB 131-18 is specific for human MBL (mannan-binding lectin) from plasma or serum, but cross-reacts with MBL from rat.
Immunogen
MBL purified from human donor plasma
Application
ELISA, WB
Species reactivity (positive)
Rat, Human
Species reactivity (negative)
Not determined
Subclass
IgG1/k
Gene ID
4153
Clone number
11F11
Epitope
Not determined
Content
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum.