Anti-Aprotinin

Anti-Aprotinin

Cat. No.

ABS 037-18

Product name

Anti-Aprotinin

Description

Mouse monoclonal antibody

Specificity

ABS 037-18 binds bovine aprotinin immobilized on a solid phase or free in solution. 

Immunogen

Aprotinin from bovine lung

Application

ELISA, WB

Species reactivity (positive)

Bovine

Species reactivity (negative)

Not determined

Subclass

IgG1/k

Gene ID

404172

Clone number

18

Epitope

The epitope of ABS 037-18 is different from the epitopes of ABS 037-21 and ABS 037-35

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein-A purified

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Aprotinin, also called bovine pancreatic trypsin inhibitor, is a single chain globular Kunitz-type serine proteinase inhibitor found in bovine pancreas, parotid gland and lung. It forms stable, enzymatically inactive complexes with trypsin, chymotrypsin, plasmin and kallikrein. Aprotinin has been used therapeutically as an antifibrinolytic agent under the name Trasylol (Bayer) to reduce blood loss during cardiopulmonary bypass surgery but this use has been associated with an increased frequency of acute renal injury.