4-8ºC without exposure to light. No precautions necessary during handling.
克隆性:
多克隆
标记物:
见说明书
适应物种:
见说明书
保质期:
12个月
抗原来源:
Human
目录编号:
ABS 017-20
级别:
见说明书
库存:
大量
供应商:
上海信裕生物科技有限公司
宿主:
Human
应用范围:
ELISA, WB, IHC, IF
浓度:
见说明书
靶点:
见说明书
抗体英文名:
Anti-Gelsolin
抗体名:
Anti-Gelsolin (human)
规格:
200ug/1mg
Anti-Gelsolin (human)
Cat. No.
ABS 017-20
Product name
Anti-Gelsolin (human)
Description
Mouse monoclonal antibody
Specificity
ABS 017-20 binds human gelsolin
Immunogen
Gelsolin purified from human plasma
Application
ELISA, WB, IHC, IF
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass
IgG1/k
Gene ID
2934
Clone number
20
Epitope
Not determined
Content
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Gelsolin participates in the extracellular actin scavenger system, binding actin and disaggregating filamentous actin released from dying cells. Actin monomers are then transferred to Gc-globulin. The plasma concentration of gelsolin is reduced in conditions of major actin release, such as acute liver failure, major trauma and rhabdomyolysis, where multi-organ failure is a risk. It has been suggested that gelsolin, like Gc-globulin, can be a prognostic factor in these conditions.