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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
见官方网站
- 亚型:
见官方网站
- 形态:
冻干粉或液体
- 保存条件:
-20ºC
- 克隆性:
多克隆
- 标记物:
见官方网站
- 适应物种:
见官方网站
- 保质期:
1年
- 抗原来源:
见官方网站
- 目录编号:
ABS 014-220
- 级别:
见官方网站
- 库存:
30
- 供应商:
上海泽叶生物科技有限公司
- 宿主:
Human
- 应用范围:
ELISA
- 浓度:
1 mg/ml
- 靶点:
见官方网站
- 抗体英文名:
Anti-TAT (Thrombin-antithrombin)
- 抗体名:
Anti-TAT (Thrombin-antithrombin)
- 规格:
200ug
Anti-TAT (Thrombin-antithrombin)
Bioporto是一家体外诊断公司,专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站:www.bioporto.com
- Cat. No.
- ABS 014-220
- Product name
- Anti-TAT (Thrombin-antithrombin)
- Description
-
Mouse monoclonal antibody
- Specificity
-
ABS 014-22 is specific for human Thrombin-antithrombin (TAT) complexes
- Immunogen
-
Thrombin-antithrombin (TAT) complexes
- Application
- ELISA
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
-
IgG1/k
- Gene ID
- 2147
- Clone number
- 22
- Epitope
-
Not determined
- Content
-
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
- Thrombin (Factor IIa) is an enzyme, a serine protease, which participates in blood clotting. It is formed when prothrombin (Factor II) is proteolytically cleaved to form thrombin, which is glycoprotein formed by two peptides chains of 36 and 259 amino acids. Thrombin converts soluble fibrinogen into insoluble strands of fibrin and is then neutralized by antithrombin in order to for a thrombin-antithrombin (TAT) complex.
- Application 1
-
ELISA
In a sandwich ELISA setup, ABS 014-222 acts as a capture antibody in conbination with HYB 230-01B as the detection antibody to measure TATcomplexes.

The calibration curve of a sandwich assay for TAT (Thrombin-antithrombin) using ABS 014-22 as capture antibody and HYB 230-01B as the biotinylated detection antibody.
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文献和实验liufengxi HIV-1 Tat (47-57) N-term Cys 序列 H-CYGRKKRRQRRR-NH2 ;原始HIV-1 Tat (47-57)序列为YGRKKRRQRRR 。N端的半胱氨酸修饰是为了利用其含有的巯基和其他分子反应,但是C端得-NH2的修饰是什么目的呢?有这个修饰的必要吗?是为了增强多肽的活性,还是发挥一个阻断活性COOH的作用? 附件是关于HIV-1 Tat (47-57) N-term Cys的产品介绍。请高手
Antithrombin (AT) is a heparin cofactor and a member of the serine protease inhibitor family (serpin). The mature AT molecule is composed of 432 amino acids and it is produced mainly in the liver. Initially, several different AT activities
Generation of thrombin has been established as the critical process leading to coagulation in vivo. Indeed, ex vivo markers of thrombin generation in patients have been useful in detecting thrombosis, while many standard global clot-time
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