Anti-H-Ficolin (human)

Anti-H-Ficolin (human)

Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。
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Cat. No.

RIG 334-012B

Product name

Anti-H-Ficolin (human)

Description

Mouse monoclonal antibody, biotinylated

Specificity

RIG 334-01 reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin.

Immunogen

Recombinant human H-ficolin 

Application

ELISA

Species reactivity (positive)

Human

Species reactivity (negative)

Not determined

Subclass

IgG1/k

Gene ID

8547

Clone number

FCN334

Epitope

Not determined

Content

100 µL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Biotinylated

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region. 

Application 1

ELISA
RIG 334-01 reacts with recombinant H-ficolin coated directly onto the microtiter well. A sandwich ELISA for H-ficolin uses RIG 334-01 for both capture and detection (1).