- $410
- BioPorto
- 丹麦
- HYB 232-111
- 2025年07月11日
- ELISA, WB( not applicable)
- Human
- 见官方网站
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
冻干粉或液体
- 保存条件：
-20ºC
- 克隆性：
多克隆
- 标记物：
见官方网站
- 适应物种：
见官方网站
- 保质期：
1年
- 抗原来源：
见官方网站
- 目录编号：
HYB 232-111
- 级别：
见官方网站
- 库存：
30
- 供应商：
上海泽叶生物科技有限公司
- 宿主：
Human
- 应用范围：
ELISA, WB( not applicable)
- 浓度：
1 mg/ml
- 靶点：
见官方网站
- 抗体英文名：
Anti-Protein S (human)
- 抗体名：
Anti-Protein S (human)
- 规格：
200ug
Anti-Protein S (human)
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- HYB 232-111
- Product name
- Anti-Protein S (human)
- Description
- Mouse monoclonal antibody
- Specificity
- HYB 232-11 is specific for human protein S.
- Immunogen
- Protein S isolated from human plasma
- Application
- ELISA, WB ( not applicable)
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
- IgG2b/k
- Gene ID
- 5627
- Clone number
- 8D5
- Epitope
- Not determined
- Content
- Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
- Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/ml, with a half-life of approximately two days. About 40% of protein S in plasma is in a free form, wheraes 60% is complexed with C4b-binding Protein (C4BP). Only the free protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
- Application 1
-
ELISA
HYB 232-11 reacts strongly with protein S. A strong reaction is seen in sandwich ELISA in combination with a biotinlabeled antibody against protein S. - Application 2
-
WB
Reactivity is Ca++ dependent and is optimal when using a tris-buffer containing 1 mM CaCl2. In Dot blotting SDS-treatment abolishes the reactivity.
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文献和实验Analysis of the Protein S Gene in Protein S Deficiency
Protein S (PS) is a 71-kDa vitamin K-dependent glycoprotein first identified in human plasma by DiScipio and colleagues in 1977 (1 ), a year after the discovery of the anticoagulant protein C (PC) (2 ,3 ). A few years later, Walker
Protein S (PS) is a vitamin K-dependent plasma glycoprotein. Around 60–70% of PS in plasma is noncovalently bound to C4-binding protein (C4BP). Free PS functions as a cofactor that enhances the activity of activated protein C (APC
a simple ELISA method to detect human anti-antibody response.
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