重组小鼠TIM-3厂商

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组小鼠TIM-3厂商，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组小鼠TIM-3厂商
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3
品牌：百奥莱博
编号：JN1459
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg20-Arg191在C端带有Fc标签。

TIM-3 质量控制：＞95%(还原性SDS-PAGE)

TIM-3 制剂：冻干品

TIM-3 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TIM-3 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TIM-3 ：
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.

我公司的重组小鼠TIM-3厂商，性价比高，货期短，送货上门，欢迎您来电咨询购买，另外，我公司还生产供应销*(代"售")下列产品：
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重组小鼠TIM-3厂商关键词：JN1459,重组TIM-3,百奥莱博,重组小鼠TIM-3蛋白,Recombinant Mouse T cell Immunoglobulin and Mucin

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重组小鼠TIM-3厂商关键词：JN1459,重组TIM-3,百奥莱博,重组小鼠TIM-3蛋白,Recombinant Mouse T cell Immunoglobulin and Mucin


·重组人小泛素相关修饰物1(SUMO1)
编号：JN1957
英文名称：Recombinant Human Small Ubiquitin-Related Modifier 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Val101在N端含有His标签。

SUMO1质量控制：＞95%(还原性SDS-PAGE)

SUMO1制剂：冻干品

SUMO1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SUMO1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SUMO1：
Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.

我公司生产供应销*(代"售")的分子生物学试剂产品正全系列现货促销，满分期待您的垂询选购重组小鼠TIM-3厂商。