相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保质期:
两年
- 英文名:
Indirubin
- 库存:
99
- 供应商:
江蓝纯
- CAS号:
479-41-4
- 规格:
10mg
属性
| 敏感性 | 对热敏感 |
| 密度 | 1.4170 |
| 溶解性 | Soluble in DMSO(warmed) (>2 mg/ml). |
| 存贮条件 | 储存温度2-8℃ |
描述
| 产品介绍 | Indirubin, also known as isoindigotin, is an inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50 = 10μM), CDK2/cyclin A (IC50 = 2.2μM), CDK2/cyclin E (IC50 = 7.5μM), CDK4/cyclin D1 (IC50 = 12μM), CDK5/p35 (IC50 = 5.5μM)) and of GSK-3β (IC50 = 600nM). Studies investigating functional isoindigos show that they have the ability to disrupt cell growth and proliferation. The compound is a potent aryl hydrocarbon receptor ligand and is found in human urine and fetal bovine serum. Synthesized isoindigo-based oligothiophenes are used to study heterojunction solar cells. Shown to inhibit allergic contact dermatitis by regulating T helper mediated immune system in a DNCB-induced model. |
| 别名 | 靛红 ;Indigo Red; Isoindogotin |
| 应用 | An inhibitor of GSK-3β and cyclin-dependent kinases. |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验≥95 ≥90 0 20 ≥90 ≥85 1 48
培养 24 - 48 h,细胞汇合度达到 80% - 95% 左右时收取上清,该上清液即可用于提取外泌体。 使用外泌体专用无血清培养基: 待细胞汇合度~50%时,移去原有完全培养基,添加新培养基进行培养,新培养基由 50% 外泌体专用无血清培养基 + 50% 完全培养基组成; 待细胞生长汇合度约为70-80%时,移去培养基; 使用1×PBS溶液将细胞润洗2-3次; 加入外泌体专用无血清培养基继续培养24 - 48 h,待细胞汇合度到 80% - 95% 时收取细胞培养上清液,该上清液即可用于外泌
Advantages Cat. No. Taq DNA Polymerase •Sequencing•Safeguarding sample•In vitro transcription TOPO® Cloning(5 minutes) Topoisomerase TOPO TA Cloning® Kit •≥95
技术资料暂无技术资料 索取技术资料






