- ￥3000 - 3999
- Abbiotec
- 美国
- 251453
- 2025年11月24日
- E, WB, IHC, IP
- Rabbit
- H, M, R, B, Ck
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GRK1.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R, B, Ck
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GRK1.
- 目录编号：
251453
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC, IP
- 浓度：
见详细说明信息
- 靶点：
Rhodopsin kinase (GRK1)
- 抗体英文名：
Rhodopsin kinase (GRK1) Antibody
- 抗体名：
Rhodopsin kinase (GRK1) Antibody
- 规格：
0.1 mg
Rhodopsin kinase (GRK1) Antibody产品详细介绍：
| 产品名称： | Rhodopsin kinase (GRK1) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 251453 |
| 规格： | 0.1 mg |
| 产品描述： | G protein-coupled receptor kinase 1 (GRK1, rhodopsin kinase) phosphorylates rhodopsin thereby initiating its deactivation. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination. Defects in GRK1 are a cause of congenital stationary night blindness Oguchi type 2 (CSNBO2). It is a non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GRK1. |
| 适用物种： | H, M, R, B, Ck |
| 应用范围： | E, WB, IHC, IP |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500 |
| 别名： | GRK1; G protein-coupled receptor kinase 1; Rhodopsin kinase; RK; RHOK |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Assay of G Protein-Coupled Receptor Kinase Activity by Rhodopsin Phosphorylation
Agonist occupation of G protein-coupled receptors (GPCRs) leads to a cellular response that wanes, or desensitizes, with prolonged agonist exposure. Different cellular mechanisms contribute to desensitization, including the altered function
In Vitro Biochemical Assays to Monitor Rhodopsin Function
in resetting rhodopsin and the phototransduction cascade involves the phosphorylation of light-active rhodopsin by rhodopsin kinase. Here, we describe assays to monitor the function of rhodopsin or rhodopsin mutants.
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