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- 详细信息
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Heat-Responsive Protein 12
- 库存:
899
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产供应重组人热反应蛋白12(HRSP12) 分子生物学试剂,我公司销*(代"售")全品类的分子生物学试剂,价格优惠,欢迎广大科研工作者垂询订购。
名称:重组人热反应蛋白12(HRSP12) 分子生物学试剂
产地:国产|进口
英文名:Recombinant Human Heat-Responsive Protein 12
品牌:百奥莱博
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Leu137在N端含有His标签。
HRSP12质量控制:>95%(还原性SDS-PAGE)
HRSP12制剂:液体
HRSP12保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于HRSP12:
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines comp*(代"a")red with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
重组人热反应蛋白12(HRSP12) 分子生物学试剂极具性价比,此外,我公司正火爆促销以下产品:
·重组人S100B
编号:JN1473
英文名称:Recombinant Human S100 Calcium Binding Protein B
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Glu92在N端含有His标签。
S100B质量控制:>95%(还原性SDS-PAGE)
S100B制剂:冻干品
S100B保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
S100B复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于S100B:
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytes are the major cells producing S100-B protein in gray matter, as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop, enabling timely delivery of crucial medical intervention before irreversible damage occurs. In addition, S100-B, which is also present in human melanocytes, is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.
重组人热反应蛋白12(HRSP12) 分子生物学试剂关键词:重组人HRSP12,重组热反应蛋白12,重组人热反应蛋白12蛋白,JN2026
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重组人热反应蛋白12(HRSP12) 分子生物学试剂关键词:重组人HRSP12,重组热反应蛋白12,重组人热反应蛋白12蛋白,JN2026
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