北京重组小鼠CD40(TNFRSF5)说明书

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产供应北京重组小鼠CD40(TNFRSF5)说明书，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：北京重组小鼠CD40(TNFRSF5)说明书
产地：国产|进口
品牌：百奥莱博
编号：JN0512
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu20-Arg193在C端含有His标签。

CD40/TNFRSF5质量控制：＞95%(还原性SDS-PAGE)

CD40/TNFRSF5制剂：冻干品

CD40/TNFRSF5保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD40/TNFRSF5复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD40/TNFRSF5：
CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.

欲了解更多北京重组小鼠CD40(TNFRSF5)说明书的品牌、产地、价格及说明书等产品信息，请致电北京百奥莱博科技有限公司，我们将竭诚为您服务，另外，以下产品正在火爆促销:

·重组人*粘附素11(*粘蛋白11)(*黏着蛋白11)(Cadherin-11)(CDH11)
编号：JN0821
英文名称：Recombinant Human Cadherin-11
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Phe23-Thr617在C端含有His标签。

CDH11质量控制：＞95%(还原性SDS-PAGE)

CDH11制剂：冻干品

CDH11保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CDH11复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CDH11：
Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.


北京重组小鼠CD40(TNFRSF5)说明书关键词：重组CD40,重组小鼠TNFRSF5,重组小鼠CD40,JN0512,重组小鼠CD40蛋白


·重组人LOXL2(类赖*酰氧化酶2)(赖*酰氧化酶样蛋白2)
编号：JN1654
英文名称：Recombinant Human Lysyl Oxidase Homolog 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln26-Gln774在C端带Avi-His标签。

LOXL2质量控制：＞95%(还原性SDS-PAGE)

LOXL2制剂：液体

LOXL2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于LOXL2：
Lysyl oxidase homolog 2 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity. The N-terminus is poorly conserved and may imp*(代"a")rt additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels. LOXL2 is an enzyme that is up-regulated in several types of cancer and is associated with a poorer prognosis. LOXL2 changes the structure of histonesand thus changes the shape of the cells, making it easier for the cancer cells to metastasize.


北京重组小鼠CD40(TNFRSF5)说明书关键词：重组CD40,重组小鼠TNFRSF5,重组小鼠CD40,JN0512,重组小鼠CD40蛋白

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