重组人FCER2(CD23)北京厂家

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人FCER2(CD23)北京厂家在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人FCER2(CD23)北京厂家
规格：10μg|50μg|500μg|1mg
产地：国产|进口
英文名：Recombinant Human Low Affinity Fc Epsilon RII
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp48-Ser321在N端带有His标签。

FCER2/CD23质量控制：＞95%(还原性SDS-PAGE)

FCER2/CD23制剂：冻干品

FCER2/CD23保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

FCER2/CD23复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于FCER2/CD23：
Low affinity immunoglobulin epsilon Fc receptor(CD23) is a secreted and single-pass type II membrane protein which is also exists as a soluble excreted form. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. Unlike many of the antibody receptors, CD23/FCER2 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. In flow cytometry, CD23/FCER2 is helpful in the differentiation of chronic lymphocytic leukemia (CD23-positive) from mantle cell leukemia (CD23-negative). CD23/FCER2 can also be demonstrated in germinal centre B-cells using immunohistochemistry, but it is not present in the resting cells of the surrounding mantle zone. CD23/FCER2 has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specificantigen).

更多有关重组人FCER2(CD23)北京厂家的价格及使用说明等，请联系我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组小鼠IFN-gamma R1(CD119)(C端含His标签)
编号：JN1411
英文名称：Recombinant Mouse Interferon gamma Receptor 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala26-Asp253在C端含有His标签。

IFN-gamma R1/CD119质量控制：＞95%(还原性SDS-PAGE)

IFN-gamma R1/CD119制剂：冻干品

IFN-gamma R1/CD119保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IFN-gamma R1/CD119复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IFN-gamma R1/CD119：
The tetrameric receptor complex for IFNγ consists of two subunits, IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ), through which the dimeric IFN-γ exerts its biological functions, including antiviral, antiproliferation and immune-modulatory activity in mammals. Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family. FNGR1, widely expressed in most host cells, is essential for IFNγ binding, receptor trafficking, and signal transduction. IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site, a signal transducer and activator of transcription 1 (STAT1) binding site. The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs).


重组人FCER2(CD23)北京厂家关键词：重组人FCER2蛋白,JN1642,重组人CD23,重组FCER2


·重组人SIAE(唾液酸O-乙酰酯酶)
编号：JN0808
英文名称：Recombinant Human Sialate O-Acetylesterase
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ile24-Lys523在C端含有His标签。

SIAE质量控制：＞95%(还原性SDS-PAGE)

SIAE制剂：液体

SIAE保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于SIAE：
Sialate O-Acetylesterase (SIAE) belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. SIAE is widely expressed with high expression levels in the testis, prostate, and colon. SIAE catalyzes N-acetyl-O-acetylneuraminate and H2O to N-acetylneuraminate and acetate. SIAE removes O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. SIAE down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for immunological tolerance. Loss of function mutations in SIAE are much more frequently found in humans with autoimmune diseases especially rheumatoid arthritis and type 1 diabetes.


重组人FCER2(CD23)北京厂家关键词：重组人FCER2蛋白,JN1642,重组人CD23,重组FCER2


·重组人ASXL1
编号：JN1040
英文名称：Recombinant Human Additional sex combs-like protein 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Lys1477-Arg1541在N端带有GST标签。

ASXL1质量控制：＞95%(还原性SDS-PAGE)

ASXL1制剂：冻干品

ASXL1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ASXL1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ASXL1：
Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.

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