重组小鼠RANK L(TNFSF11)厂家

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组小鼠RANK L(TNFSF11)厂家，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组小鼠RANK L(TNFSF11)厂家
英文名：Recombinant Mouse TNF ligand superfamily member 11
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
产地：国产|进口
编号：JN0506
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Gln137-Asp316表达纯化得来。

RANK L/TNFSF11质量控制：＞95%(还原性SDS-PAGE)

RANK L/TNFSF11制剂：冻干品

RANK L/TNFSF11保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

RANK L/TNFSF11复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于RANK L/TNFSF11：
Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.

我公司的重组小鼠RANK L(TNFSF11)厂家，性价比高，货期短，送货上门，欢迎您来电咨询购买，另外，我公司还生产供应销*(代"售")下列产品：

·重组人趋化因子CXCL3(GROγ)
编号：JN0301
英文名称：Recombinant Human C-X-C Motif Chemokine 3
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Ala35-Asn107在N端含有His标签

CXCL3/GRO gamma质量控制：＞95%(还原性SDS-PAGE)。

CXCL3/GRO gamma制剂：冻干品

CXCL3/GRO gamma保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CXCL3/GRO gamma复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CXCL3/GRO gamma：
C-X-C Motif Chemokine 3 (CXCL3) is a secreted protein that belongs to the intercrine alpha (chemokine CXC) family. CXCL3 controls the migration and adhesion of monocytes and mediates its effect on its target cell by interacting with a cell surface chemokine receptor called CXCR2. In addition, CXCL3 is thought to play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.


重组小鼠RANK L(TNFSF11)厂家关键词：重组小鼠TNFSF11,JN0506,重组小鼠RANK L蛋白,重组RANK L


·哺乳动物细胞蛋白抽提试剂
编号：JN0189
规格：100ml|500ml
  哺乳动物细胞总蛋白抽提试剂是一种采用温和表面活性剂的细胞裂解试剂，该试剂在低浓度即能溶解细胞膜，不会引起蛋白质变性，抽提的蛋白可用于进一步的分析检测实验或下游的分离纯化。利用本产品抽提效率极高，得到的蛋白量高于反复冻融法或者超声法。本产品对悬浮或贴壁生长的细胞都有很高的抽提效率，无需将贴壁细胞进行消化收集。

·重组狨T细胞免疫球蛋白黏蛋白分子3(TIM-3)
编号：JN1512
英文名称：Recombinant Marmoset T cell Immunoglobulin and Mucin Domain-3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu24-Ile193在C端含有His标签。

TIM-3 质量控制：＞95%(还原性SDS-PAGE)

TIM-3 制剂：冻干品

TIM-3 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TIM-3 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TIM-3 ：
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.


重组小鼠RANK L(TNFSF11)厂家关键词：重组小鼠TNFSF11,JN0506,重组小鼠RANK L蛋白,重组RANK L


·重组人PTPRN(蛋白酪*酸磷酸酶受体型N)
编号：JN1779
英文名称：Recombinant Human Islet Cell Antigen 2/Protein Tyrosine Phosphatase Receptor-type N
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Arg576-Gln950在N端含有His标签。

PTPRN质量控制：＞95%(还原性SDS-PAGE)

PTPRN制剂：液体

PTPRN保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PTPRN：
Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendo*(代"c")rine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendo*(代"c")rine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendo*(代"c")rine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2.This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.

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