重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)厂家由专业试剂供应商北京百奥莱博提供，用于生化研究，本产品质量好，且极具价格优势，深为用户称道，了解更多重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)等分子生物学试剂产品请联系我司咨询订购。

名称：重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)厂家
品牌：百奥莱博
编号：JN0504
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse Apoptosis-mediating Surface Antigen FAS
产地：国产|进口
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln22-Arg169在C端带有Fc标签。

Fas/TNFRSF6/CD95质量控制：＞95%(还原性SDS-PAGE)

Fas/TNFRSF6/CD95制剂：冻干品

Fas/TNFRSF6/CD95保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Fas/TNFRSF6/CD95复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Fas/TNFRSF6/CD95：
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected in various tissues including thymus, liver, lung, heart, and adult ovary. As a receptor for TNFSF6/FASLG, The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

除重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)厂家外，我公司正在打折促销以下产品：

·重组人激活素受体2B(ACVR2B)
编号：JN0705
英文名称：Recombinant Human Activin Receptor Type 2B
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser19-Thr134在C端含有His标签。

ACVR2B质量控制：＞95%(还原性SDS-PAGE)

ACVR2B制剂：冻干品

ACVR2B保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ACVR2B复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ACVR2B：
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities.


重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)厂家关键词：重组小鼠CD95,重组小鼠TNFRSF6,重组小鼠Fas,JN0504,C端Fc标签


·重组人白介素IL-15(白细胞介素15)
编号：JN0336
英文名称：Recombinant Human Interleukin-15
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Asn49-Ser162表达纯化而来。

IL-15质量控制：＞95%(还原性SDS-PAGE)。

IL-15制剂：冻干品

IL-15保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-15复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-15：
Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other"s activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.


重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)厂家关键词：重组小鼠CD95,重组小鼠TNFRSF6,重组小鼠Fas,JN0504,C端Fc标签


·重组人EphA2
编号：JN1572
英文名称：Recombinant Human Ephrin A Receptor 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala24-Asn534在C端带有Fc标签。

EphA2质量控制：＞95%(还原性SDS-PAGE)

EphA2制剂：冻干品

EphA2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

EphA2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于EphA2：
Ephrin type-A receptor 2/EphA2 is a member of the Eph receptor tyrosine kinase family which binds Ephrins A1, 2, 3, 4, and 5. A and B class Eph proteins have a common structural organization. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. EphA2 becomes autophosphorylated following ligand binding and then interacts with SH2 domain-containing PI3-kinase to activate MAPK pathways. Reverse signaling is also propagated through the Ephrin ligand. Transcription of EphA2 is dependent on the expression of E-Cadherin, and can be induced by p53 family transcription factors. EphA2 is upregulated in breast, prostate, and colon cancer vascular endothelium. Its ligand, EphrinA1, is expressed by the local tumor cells. In some cases, EphA2 and EphrinA1 are expressed on the same blood vessels. EphA2 signaling cooperates with VEGF receptor signaling in promoting endothelial cell migration.

我公司正在火爆促销分子生物学试剂系列产品，欢迎您的垂询选购重组小鼠Fas(TNFRSF6)(CD95)(C端Fc标签)厂家。