Recombinant Human SEMA4B (C-6His) (CB69)
产品说明(Description)
Recombinant Human Semaphorin 4B is produced by our Mammalian expression system and the target gene encoding Leu44-Glu717 is expressed with a 6His tag at the C-terminus.
Accession #: Q9NPR2
Known as: Semaphorin-4B; KIAA1745; SEMAC and SEMA4B
制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
质量控制(Quality Control)
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
运输(Shipping)
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
保存(Storage)
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
背景(Background)
The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
电泳(SDS-PAGE)
FOR RESEARCH USE ONLY