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- 近岸蛋白(Novoprotein)
- 中国
- C010
- 2026年01月22日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 英文名：
Recombinant Human PTH/Parathyroid Hormone
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥840.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥2520.0 |
| 规格： | 500ug | 产品价格： | 询价 |
| 规格： | 1mg | 产品价格： | 询价 |
Recombinant Human PTH/Parathyroid Hormone (C010)
产品说明(Description)
Recombinant Human Parathyroid Hormone is produced by our E.coli expression system and the target gene encoding Ser32-Gln115 is expressed.
Accession #: P01270
Known as: Parathyroid Hormone; PTH; Parathormone; Parathyrin
制剂（Formulation）
Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0.
质量控制（Quality Control）
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
复溶（Reconstitution）
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存（Storage）
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
背景（Background）
Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.
电泳(SDS-PAGE)
参考文献(Reference)
1、Extraction and purification of recombinant intact human Parathyroid Hormone (hPTH) from bacterial cell. Adnan E. Al-badran. et al. Journal of Biomedical Engineering and Informatics. 2017.
FOR RESEARCH USE ONLY
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文献和实验甲状旁腺激素（parathyroid hormone，PTH）
甲状旁腺主细胞分泌的肽类激素。正常人血浆PTH含量约1毫微克/毫升，最高可达6毫微克/毫升。其主要靶器官是骨、肾和小肠，调节钙、磷代谢，最终效应是升血钙，降低血磷：（1）对骨的作用。PTH刺激骨质吸收，动员骨的钙、磷入血。可分为快速效应和慢速效应两个时相。快速效应数分钟内即可发生，作用于骨细胞膜系统。骨细胞膜系统是由骨细胞和成骨细胞组成的一层膜，除破骨细胞邻近的区域外，覆盖全部骨表面和腔隙表面，从而在骨质与细胞外液之间形成可通透性屏障。这层膜与骨质之间有少量滑液，细胞外液侧
Construction of Recombinant Human Cytomegalovirus
The use of reverse genetics to generate recombinant viruses allows the researcher to investigate the exact functional significance of particular viral genes during the virus life cycle, by means of their deletion or modification in the viral
In Vivo Parathyroid Hormone Treatments and RNA Isolation and Analysis
Intermittent parathyroid hormone (PTH) administration increases bone formation and bone mass and is being used as a therapy for osteoporosis. By contrast, chronic hyperparathyroidism results in the metabolic bone disease osteitis fibrosa
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