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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Recombinant Human Natural Cytotoxicity Triggering Receptor 1/NKp46/NCR1
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥840.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥2520.0 |
| 规格: | 500ug | 产品价格: | 询价 |
| 规格: | 1mg | 产品价格: | 询价 |
Recombinant Human Natural Cytotoxicity Triggering Receptor 1/NKp46/NCR1 (C763)
产品说明(Description)
Recombinant Human Natural Cytotoxicity Triggering Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln22-Asn254 is expressed with a Fc tag at the C-terminus.
Accession #: AAH64806
Known as: Natural cytotoxicity triggering receptor 1;Lymphocyte antigen 94 homolog;NK cell-activating receptor;Natural killer cell p46-related protein;NK-p46;NKp46;hNKp46;CD335;NCR1;LY94;
制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
质量控制(Quality Control)
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
背景(Background)
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow.
电泳(SDS-PAGE)
FOR RESEARCH USE ONLY
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文献和实验Construction of RibonucleaseAntibody Conjugates for Selective Cytotoxicity
or an antibody directed against the human transferrin receptor (5 ). Antibody RNase conjugates have also been shown to have potent anti-tumor activity against human glioma cells in athymic mice (6 ) and to enhance the activity of vincristine in mdr1 multidrug
Production and Characterization of Receptor-Specific TNF Muteins
receptors (TNFR) (radioligand competition binding and Biacore). The biological activity of wild-type TNF and/or TNF muteins can be assessed in cellular assays. TNF-induced cytotoxicity toward murine L929s cells and human Kym39A6 cells is mediated
and p75) (2 ). Signaling through the p55 receptor is primarily associated with responses such as cytotoxicity (2 ,3 ) and cytokine secretion (4 ) whereas the p75 receptor is responsible for lymphoproliferative signals and the activation of T-cells
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