Recombinant Human B4GALT4 (C513)
产品说明(Description)
Recombinant Human beta-1,4-Galactosyltransferase 4 is produced by our Mammalian expression system and the target gene encoding Gln39-Ala344 is expressed with a 6His tag at the C-terminus.
Accession #: O60513
Known as: Beta-1;4-Galactosyltransferase 4; Beta-1;4-GalTase 4; Beta4Gal-T4; b4Gal-T4; UDP-Gal:Beta-GlcNAc Beta-1;4-Galactosyltransferase 4; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1;4-Galactosyltransferase 4; B4GALT4
制剂(Formulation)
Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 7.5.
质量控制(Quality Control)
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
运输(Shipping)
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
保存(Storage)
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles.
背景(Background)
β-1,4-galactosyltransferase 4 (B4GALT4) is a single-pass type II membrane protein that belongs to the Glycosyltransferase 7 family. B4GALT4 consist of the following 2 domains: N-Acetyllactosamine Synthase and β-N-Acetylglucosaminyl-Glycolipid β-1,4-Galactosyltransferase. B4GALT4 is highly expressed in the heart, placenta, kidney, and pancreas; it is lowly expressed in the brain, colon, lung, muscle, ovary, testis, and uterus. B4GALT4 function is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
电泳(SDS-PAGE)
参考文献(Reference)
N-glycosylation of the human β1,4-galactosyltransferase 4 is crucial for its activity and Golgi localization[J]. Auhen Shauchuk. et al. Glycoconjugate Journal. 2020.
FOR RESEARCH USE ONLY