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- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture and light
- 英文名：
HCQ sulfate
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
747-36-4
- 规格：
10 mM * 1 mL/50 mg/100 mg/200 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥550.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥500.0 |
| 规格： | 100 mg | 产品价格： | ￥700.0 |
| 规格： | 200 mg | 产品价格： | ￥1120.0 |
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Hydroxychloroquine sulfate
CAS No. : 747-36-4
MCE 国际站：Hydroxychloroquine sulfate
产品活性：Hydroxychloroquine sulfate (HCQ sulfate) 是一种合成的抗疟疾剂，也可以抑制 Toll 样受体 7/9 (TLR7/9) 信号传导。Hydroxychloroquine sulfate 有效抑制 SARS-CoV-2 感染。
研究领域：Anti-infection | Immunology/Inflammation | Autophagy
作用靶点：Parasite | Toll-like Receptor (TLR) | SARS-CoV | Autophagy
In Vitro: Hydroxychloroquine sulfate is a synthetic antimalarial drug derived from 4-aminoquinoline; it has been used for several decades for the treatment of some rheumatic diseases such as rheumatoid arthritis (RA). Five micromolar Hydroxychloroquine sulfate or chloroquine also has no measurable effect on intracellular pH, although these concentrations can inhibit TLR9 or 7 signaling induced by DNA or RNA ligands.
In Vivo: Hydroxychloroquine sulfate is prescribed for the treatment of lupus, and both Hydroxychloroquine sulfate and its analog chloroquine inhibit TLR7 and 9 signaling.
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