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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Cardiorythmine; (+)-Ajmaline
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
4360-12-7
- 规格：
10 mM * 1 mL/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥330.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥300.0 |
| 规格： | 100 mg | 产品价格： | ￥500.0 |
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Ajmaline
CAS No. : 4360-12-7
MCE 国际站：Ajmaline
产品活性：Ajmaline (Cardiorythmine) 是一种钠通道 (sodium channel) 阻断剂，1A 类抗心律失常剂。Ajmaline 阻断 HERG 电流，在 HEK 细胞的 IC50 为 1 μM，爪蟾卵母细胞为 42.3 μM。Ajmaline 可用于室性心动过速的研究。
研究领域：Membrane Transporter/Ion Channel
作用靶点：Sodium Channel
In Vitro: Electrophysiological experiments are performed with human embryonic kidney (HEK) cells (whole-cell patch clamp) and Xenopus oocytes (double-electrode voltage clamp) expressing wild-type and mutant HERG channels. Ajmaline blocks HERG currents with an IC50 of 1.0μM in HEK cells and 42.3μM in Xenopus oocytes.
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