生物学描述 Potent dynamin I and II inhibitor. Inhibits dynamin I GTPase (IC50 = 2.3 μM) and targets pleckstrin homology (PH) (lipid binding) domain. Inhibits receptor-mediated and synaptic vesicle endocytosis (IC50 values are 9.3 and 7.1 μM, respectively).
纯度 > 98%
常规说明 Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. RTIL™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.
存放说明 Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
溶解度概述 Soluble in DMSO to 20 mM
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.