A23187 (Calcimycin)

概述

• 产品名称
  A23187 (Calcimycin)
• 描述
  Ca²⁺ ionophore
• 别名
  • calcimycin
• 生物学描述
  A mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca²⁺ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against Gram-positive bacteria.
• 纯度
  > 98%

性能

• 化学名称
  5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7- dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid
• 分子量
  523.63
• 化学结构
  
• 分子式
  C₂₉H₃₇N₃O₆
• CAS编号
  52665-69-7
• PubChem识别号
  11957499
• 存放说明
  Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in DMSO to 100 mM (with heating)
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  O=C(O)c1c(NC)ccc2oc(nc12)C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5cccn5
• 来源

  Steptomyces chartreusensis