PNU 282987

概述

• 产品名称
  PNU 282987
• 描述
  Selective α7 nAChR agonist
• 生物学描述
  Selective α7nAChR agonist. Negligible activity at α1β1γδ and α3β4 receptors. High affinity for rat α7nACh receptors (K_i = 26 nM). Functional antagonist at 5-HT₃ receptors (IC₅₀ = 4541 nM).
• 纯度
  > 99%

性能

• 化学名称
  N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride
• 分子量
  301.22
• 化学结构
  
• 分子式
  C₁₄H₁₇ClN₂O.HCl
• CAS编号
  123464-89-1
• 存放说明
  Store at Room Temperature. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in water to 100 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• 来源

  Synthetic