(S)-5-Iodowillardiine

概述

• 产品名称
  (S)-5-Iodowillardiine
• 描述
  GluK1 kainate agonist
• 生物学描述
  Selective GluK1 (formerly GluR5) kainate receptor agonist (EC₅₀ = 83 μM). Partial agonist activity at GluK2 (formerly GluR6/KA2) receptors. Displays low affinity for AMPA and homomeric GluR6 and GluR7 receptors.
• 纯度
  > 98%

性能

• 化学名称
  (S)-2-Amino-3-(5-iodo-3,4-dihydro-2,4-dioxopyrimidin-1(2H)-yl)propanoic acid
• 分子量
  325.06
• 化学结构
  
• 分子式
  C₇H₈IN₃O₄
• CAS编号
  140187-25-3
• PubChem识别号
  447196
• 存放说明
  Store at Room Temperature. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in 1 eq. NaOH to 25 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  N[C@@H](CN1C=C(I)C(=O)NC1=O)C(=O)O
• 来源

  Synthetic