生物学描述 Selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, approx. 450 and >50 μM for AMPA- , kainate- and NMDA-induced responses, respectively). Skeletal muscle relaxant, orally active anticonvulsant, neuroprotective and anxiolytic in vivo.
Also available in simple stock solutions (ab146716) - add 1 ml of water to get an exact, ready-to-use concentration.
存放说明 Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
溶解度概述 Soluble in 1eq. HCl to 10mM and in DMSO to 25 mM (with heating)
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.