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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at +4°C
- 保质期:
12 months
- 英文名:
PP2
- 供应商:
上海汇谱仪器有限公司
- CAS号:
172889-27-9
- 规格:
1 mg
概述
- 产品名称
PP2 - 描述
Src and RIP2 kinase inhibitor - 生物学描述
Inhibitor of the Src family of kinases. Inhibits Src and Lck kinase (IC50 values are 36 and 31 nM, respectively). Also shown to inhibit RIP2 and CK1δ (IC50values are 19 and 41 nM, respectively). - 纯度
> 98%
性能
- 化学名称
1-tert-Butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine - 分子量
301.78 - 化学结构

- 分子式
C15H16ClN5 - CAS编号
172889-27-9 - PubChem识别号
4878 - 存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in DMSO to 50 mM and in ethanol to 10 mM - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- SMILES
Clc1ccc(cc1)c3nn(c2ncnc(N)c23)C(C)(C)C - 来源
Synthetic
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文献和实验caga 我是临床的研究生,想做PP2A的课题,哪个强人给点意见,谢谢 chuckdouble caga wrote: 我是临床的研究生,想做PP2A的课题,哪个强人给点意见,谢谢 这个问题太抽象了,不明白你想做什么。 katerlisa 我也要做这个方向的课题,以后多交流 本文由丁香园论坛提供,想
Substrate Analysis of Arabidopsis PP2C-Type Protein Phosphatases
Protein phosphorylation by protein kinases can be reversed by the action of protein phosphatases. In plants, the Ser/Thr-specific phosphatases dominate among the protein phosphatase families with the type 2C protein phosphatases (PP2Cs
lingwu 酪氨酸激酶抑制剂PP1和PP2有什么区别?如何选择, 急切想知道,谢谢! ylhuang0502 首先纠正一下, PP1和PP2都不是酪氨酸激酶的通用抑制剂,两者均为Src family kinase的选择性抑制剂。其中PP2更常用些,两者的差异很小,化学结构非常相似,两者均不是Src family kinase 特异性抑制剂,两者均可抑制别的激酶的活性,,比如: The Src
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