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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2)
- 规格:
25次分析
产品名称:CD54 (ICAM1) FITC单克隆抗体 (克隆号15.2)|CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2)
【产品形式】:艾美捷为您提供的CD54 (ICAM1) FITC单克隆抗体 (克隆号15.2)产品为无色液体.建议使用冰袋运输,收到产品后,请4°C储存.该产品有效期为12个月.
【背景资料】:Inter-Cellular Adhesion Molecule 1 (ICAM-1), also known as Cluster of Differentiation 54 (CD54), is a member of the immunoglobulin superfamily, and is a cell surface glycoprotein which is typically expressed in low concentrations on endothelial cells and cells of the immune system. The protein encoded by this gene is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFα) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrate into tissues. ICAM-1 has been implicated in subarachnoid hemorrhage (SAH). Levels of ICAM-1 are shown to be significantly elevated in patients with SAH over control subjects in many studies. ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds. The 15.2 antibody reacts with the 85-110 kDa ICAM-1.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:CD54 (ICAM1) FITC单克隆抗体 (克隆号15.2),查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:CD54 ,CD54 (ICAM1) FITC单克隆抗体 (克隆号15.2)
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文献和实验杂交瘤技术又称单克隆抗体技术(monoclonal antibody technique)
1975年,Kohler和Milstein发现将小鼠骨髓瘤细胞和绵羊红细胞免疫的小鼠脾细胞进行融合,形成的杂交细胞既可产生抗体,又可无限增殖,从而创立了单克隆抗体杂交瘤技术。这一技术上的突破不仅为医学与 生物 学基础研究开创了新纪元,也为临床疾病的诊断、预防和治疗提供了新的方法。 1. 杂交瘤的基本原理 杂交瘤技术又称单克隆抗体技术(monoclonal antibody technique)。杂交瘤技术是使免疫
secondary antibody review -- data from 99 publications
Laboratories 15 AP western blot 15 rhodamine immunocytochemistry 1:500 15 FITC immunocytochemistry 16 sheep Alexa Fluor 568 immunocytochemistry 1:250 Invitrogen 16 streptavidin-horseradish peroxidase
Dual- and Triple-Color Fluorospot
in several publications and reagents/kits for various cytokine combinations and species are commercially available. The most common protocol for fluorospot includes the use of biotinylated detection antibodies for one cytokine and an FITC-labeled detection antibody
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