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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
Bad monoclonal Antibody
- 规格:
100 ug
产品名称:Bad单克隆抗体|Bad monoclonal Antibody
【产品形式】:艾美捷为您提供的Bad单克隆抗体产品为无色液体.建议使用冰袋运输,收到产品后,请-20°C储存.该产品有效期为12个月.
【背景资料】:Bad is a member of the Bcl-2 family proteins. Within the Bcl-2 homology domains 1 and 2 (BH1 and BH2), Bad shows significant homology to Bcl-2 and Bcl-x. Bcl-2 is known to block several apoptosis signals and is considered to be a central downstream cell death repressor. Bcl-XL represses apoptosis, but its short form, Bcl-XS, promotes cell death. Bax is known to homodimerize as well as heterodimerize with Bcl-2. An excess concentration of Bax opposes the ability of Bcl-2 to repress cell death. Bad can selectively dimerize with Bcl-xL and Bcl-2, but not with Bax, Bcl-xS, Mcl-1, A1, or itself. In mammalian cells, Bad binds more strongly to Bcl-xL than Bcl-2, which may explain why Bad reverse the death repressor activity of Bcl-xL, but not that of Bcl-2. The formation of the Bad-Bcl-xL heterodimer displaces Bax and restores favorable conditions for apoptosis.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:Bad单克隆抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:Bad,Bad单克隆抗体
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文献和实验指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma,在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应,对应于抗原之不同部分可制成各种不同的抗体复合体。然而,因为一个产生抗体的细胞,只能产生一种抗体,所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种,可形成边产生抗体边增殖的 hybridoma,将每个杂种细胞进行克隆(无性繁殖系)培养,则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成,这样得到的就是单克隆抗体。此抗体在测定
Monoclonal Antibody Production
Order 6 six week old Balb/C mice and let the ARC know they are coming.Have your antigen ready for when they arrive.Once they get there earmark the mice and perform a pre-bleed on them to be used as an ELISA control for monitoring the titer
Monoclonal Antibody-Based Immunoassays
An immunoassay may be defined as an assay that employs an immunological reagent, usually an antibody, to confer specificity for the ligand being measured. As a corollary to this, the discovery, and subsequent development, of monoclonal
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