T-00127_HEV1

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T-00127_HEV1

CAS No. : 900874-91-1

MCE 国际站：T-00127_HEV1

产品活性：T-00127_HEV1 是一个 phosphatidylinositol 4-kinase III beta (PI4KB) 抑制剂，其 IC₅₀ 值为 60 nM。

研究领域：PI3K/Akt/mTOR

作用靶点：PI4K

In Vitro: T-00127_HEV1 shows more potent anti-poliovirus (PV) activity (EC₅₀ of 0.77 μM) than other candidate compounds (EC₅₀ of 1.7 to 4.7 μM). GW5074 and T-00127_HEV1 almost completely inhibit PI4KB kinase activity at 10 μM (3% and 5% of residual activity, respectively), in contrast to AN-12-H5 (108% of activity [no inhibition]).

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