Vascular smooth muscle cells are the cellular substrate of most significant arterial disease. The increased growth potential of vascular smooth muscle cells represents one of the crucial anomalies responsible for the development of essential vascular diseases. New studies demonstrate that vascular smooth muscle cells express ICAM-1 and VCAM-1, which may contribute to the inflammatory reaction in the vascular wall and may actively be involved in the progression and stability of vascular disease. In vitro culture of human VSMC as a model of vascular research played a critical role and continues providing information in the pharmacology and the therapy of vascular diseases.HUASMC from AcceGen Research Laboratories are isolated from human umbilical arteries. HUASMC are cryopreserved at the end of secondary culture and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HUASMC are characterized by immunofluorescent method with antibodies to ?-smooth muscle actin and desmin. HUASMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HUASMC are guaranteed to further expand for 15 population doublings at the condition provided by AcceGen Research Laboratories. 血管平滑肌细胞是最重要的动脉疾病的细胞基质。血管平滑肌细胞的生长潜力增加代表了导致基本血管疾病发展的关键异常之一。新的研究表明,血管平滑肌细胞表达 ICAM-1 和 VCAM-1,这可能有助于血管壁的炎症反应,并可能积极参与血管疾病的进展和稳定。人类 VSMC 的体外培养作为血管研究的模型发挥了关键作用,并继续为血管疾病的药理学和治疗提供信息。来自 AcceGen 研究实验室的 HUASMC 是从人类脐动脉中分离出来的。 HUASMC 在二次培养结束时冷冻保存并冷冻交付。每个小瓶在 1 ml 体积中包含 >5×10^5 个细胞。 HUASMC 的特点是通过免疫荧光法检测 β-平滑肌肌动蛋白和结蛋白的抗体。 HUASMC 对 HIV-1、HBV、HCV、支原体、细菌、酵母和真菌呈阴性。 HUASMC 保证在 AcceGen 研究实验室提供的条件下进一步扩大 15 倍人口。
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.