Human lungs are the primary organ for respiration and are clinically relevant to many commonly seen pulmonary diseases such as asthma, pneumonia, and lung cancer. Human lung consists of several different types of cells, including airway epithelial cells (ciliated, basal, goblet, neuroendocrine and Clara cells), alveolar cells (type I cells, type II cells, and fibroblasts in the interstitium) and pulmonary vascular cells (endothelial cells, smooth muscle cells, adventitial fibroblasts). 人的肺是主要的呼吸器官,与许多常见的肺部疾病如哮喘、肺炎、肺癌等临床相关。人肺由几种不同类型的细胞组成,包括气道上皮细胞(纤毛细胞、基底细胞、杯状细胞、神经内分泌细胞和克拉拉细胞)、肺泡细胞(I型细胞、II型细胞和间质成纤维细胞)和肺血管细胞(内皮细胞、平滑肌细胞、外膜成纤维细胞)。
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Application
For research use only Human primary lung cells provide a reliable model to accurately emulate the physiological properties of human lung in vivo. Thus, they can be applied in pharmacokinetic research for drug screening and test for toxicology. They are also good model for study pulmonary diseases, microbial infections and airway inflammations. Human pulmonary cells can be especially useful in the COVID pandemic situation. COVID-19 has shown to cause lung complications and increased susceptibility is associated with people who have chronic lung disease. Furthermore, primary lung cells can be used to develop “lung-on-a-chip” model for respiratory disease and applied to pharmacological studies. Lung cells provide a good model for study intact lung functions and physiological properties under different conditions.
Key Features
-Backed by AcceGen advanced technology -Cryopreserved for highest viability and plating efficiency -Quality-tested for accurate results