重组小鼠CD300a(LMIR1)哪里卖

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重组小鼠CD300a(LMIR1)哪里卖由专业试剂供应商北京百奥莱博提供，用于科研实验，本产品质量好，且极具价格优势，深为用户称道，了解更多重组小鼠CD300a(LMIR1)等分子生物学试剂产品请联系我司咨询订购。

名称：重组小鼠CD300a(LMIR1)哪里卖
编号：JN1897
英文名：Recombinant Mouse Leukocyte mono-Ig-like receptor 1
品牌：百奥莱博
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu28-Arg183在C端带有Fc标签。

CD300a/LMIR1质量控制：＞95%(还原性SDS-PAGE)

CD300a/LMIR1制剂：冻干品

CD300a/LMIR1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD300a/LMIR1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD300a/LMIR1：
LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.

除重组小鼠CD300a(LMIR1)哪里卖外，我公司正在打折促销以下产品：

·重组人三结构域蛋白(三重基序蛋白5)(TRIM5)
编号：JN1059
英文名称：Recombinant Human Tripartite motif-containing protein 5
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Gln248在N端含有His标签。

TRIM5质量控制：＞95%(还原性SDS-PAGE)

TRIM5制剂：液体

TRIM5保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于TRIM5：
Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation


重组小鼠CD300a(LMIR1)哪里卖关键词：JN1897,重组CD300a,重组小鼠CD300a,重组小鼠CD300a蛋白,重组小鼠LMIR1

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重组小鼠CD300a(LMIR1)哪里卖关键词：JN1897,重组CD300a,重组小鼠CD300a,重组小鼠CD300a蛋白,重组小鼠LMIR1


·重组人VSIG4(含V-set和Ig结构域蛋白4)
编号：JN0620
英文名称：Recombinant Human V-Set and Immunoglobulin Domain-Containing Protein 4
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg20-Pro283在C端含有His标签。

VSIG4质量控制：＞95%(还原性SDS-PAGE)

VSIG4制剂：冻干品

VSIG4保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

VSIG4复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于VSIG4：
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) is a 45-50 kDa macrophage-specific transmembrane glycoprotein that belongs to the B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type Ig domain and a truncated C-type Ig domain. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. It is also expressed in resting macrophages. No VSIG4 expression appears to be present in T and B cells. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. It is a potent inhibitor of the alternative complement pathway convertases. Human VSIG4 is 399 amino acids (aa) in length. It is a type I transmembrane (TM) glycoprotein that contains a 264 aa extracellular domain (ECD) (aa 20 - 283) and a 95 aa cytoplasmic region.

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