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重组人EGFR(表皮生长因子受体)品牌由专业试剂供应商北京百奥莱博提供,用于生化科研试验,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人EGFR(表皮生长因子受体)等分子生物学试剂产品请联系我司咨询订购。
名称:重组人EGFR(表皮生长因子受体)品牌
编号:JN1434
英文名:Recombinant Human Epidermal Growth Factor Receptor/Receptor Tyrosine Protein Kinase ErbB1
规格:10μg|50μg|500μg|1mg
品牌:百奥莱博
产地:国产|进口
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Val30Gly&Asn298-Ser645在C端含有His标签。
EGFR/HER1 mutant质量控制:>95%(还原性SDS-PAGE)
EGFR/HER1 mutant制剂:冻干品
EGFR/HER1 mutant保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
EGFR/HER1 mutant复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于EGFR/HER1 mutant:
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transmembrane glycoproteins with an extracellular ligand binding domain. The extracellular ligand binding domain is containing two cysteine-rich domains separated by a spacer region and a cytoplasmic domain containing a membrane-proximal tyrosine kinase domain. Ligand binding could induce EGFR homodimerization and heterodimerization with ErbB2, resulting in cell signaling, heterodimerization tyrosine phosphorylation and kinase activation. It can bind EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, epigen, and so on. Its signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGFR is overexpressed in different tumors. Several anti-cancer drugs use EGFR as target.
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重组人EGFR(表皮生长因子受体)品牌关键词:重组人EGFR,JN1434,重组EGFR,重组人表皮生长因子受体,重组人EGFR蛋白
·中分子量蛋白Marker
编号:JN0172
规格:1ml
本产品是一组纯化好的蛋白质混合物,在凝胶电泳时可呈现7条清晰的条带。蛋白分子量从大到小依次为120KD, 90KD, 60KD, 40KD, 30KD,20KD, 14KD。适用于大多数未知蛋白质分子量的测定。
使用建议:
本产品无需处理,可直接使用于PAGE电泳及Western Blot实验。Bio- Rad电泳系统,6×8cm胶,建议用量为5μl/次。收到产品后请分装后-20℃保存,尽量避免反复冻融。
储存条件:-20℃,避免反复冻融。
·重组人胶质纤维酸性蛋白(GFAP)
编号:JN1999
英文名称:Recombinant Human Glial Fibrillary Acidic Protein
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Leu292-Met432在N端含有His标签。
GFAP质量控制:>95%(还原性SDS-PAGE)
GFAP制剂:冻干品
GFAP保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
GFAP复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于GFAP:
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.
重组人EGFR(表皮生长因子受体)品牌关键词:重组人EGFR,JN1434,重组EGFR,重组人表皮生长因子受体,重组人EGFR蛋白
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