重组人高迁移率族蛋白B1(HMGB1)厂家

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人高迁移率族蛋白B1(HMGB1)厂家在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人高迁移率族蛋白B1(HMGB1)厂家
编号：JN1210
英文名：Recombinant Human High mobility group protein B1
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
产地：国产|进口
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Pro92-Val176 is expressed with a MARI tag at the N-terminus.

HMGB1质量控制：＞95%(还原性SDS-PAGE)

HMGB1制剂：冻干品

HMGB1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

HMGB1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于HMGB1：
High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.ItContains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.

我公司的重组人高迁移率族蛋白B1(HMGB1)厂家，性价比高，货期短，送货上门，欢迎您来电咨询购买，另外，我公司还生产供应销*(代"售")下列产品：

·重组小鼠RANK(TNFRSF11A)(CD265)
编号：JN0509
英文名称：Recombinant Mouse Receptor Activator of NF-kappa B
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val31-Ser214在C端含有His标签。

RANK/TNFRSF11A/CD265质量控制：＞95%(还原性SDS-PAGE)

RANK/TNFRSF11A/CD265制剂：冻干品

RANK/TNFRSF11A/CD265保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

RANK/TNFRSF11A/CD265复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于RANK/TNFRSF11A/CD265：
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member oftumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, brain and kidney, but weakly expressed in spleen and bone marrow. After binding its ligand RANKL, RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation. RANK/TNFRSF11A signaling is largely considered to be growth promoting and apoptosis reducing such as the effects observed in osteoclasts. RANK/TNFRSF11A was also found to be involved in the regulation of interactions between T-cells and dendritic cells.


重组人高迁移率族蛋白B1(HMGB1)厂家关键词：JN1210,重组人高迁移率族蛋白B1蛋白,重组人HMGB1,重组高迁移率族蛋白B1


·重组人PGK1(磷酸甘油酸激酶1)
编号：JN1254
英文名称：Recombinant Human Phosphoglycerate kinase 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser2-Ile417在C端含有His标签。

PGK1质量控制：＞95%(还原性SDS-PAGE)

PGK1制剂：液体

PGK1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PGK1：
PGK1 is called phosphoglycerate kinase that involved in a critical energy-producing process known as glycolysis. Phosphoglycerate kinase helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 The encoded protein may also act as a cofactor for polymerase alpha.. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.

·重组人CD44(MIC4)
编号：JN1870
英文名称：Recombinant Human CD44
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln21-Pro220在C端带有Fc标签。

CD44/MIC4质量控制：＞95%(还原性SDS-PAGE)

CD44/MIC4制剂：冻干品

CD44/MIC4保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD44/MIC4复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD44/MIC4：
CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.


重组人高迁移率族蛋白B1(HMGB1)厂家关键词：JN1210,重组人高迁移率族蛋白B1蛋白,重组人HMGB1,重组高迁移率族蛋白B1


·重组人醛酮还原酶家族1成员C2(AKR1C2)
编号：JN0698
英文名称：Recombinant Human Aldo-Keto Reductase Family 1 Member C2
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Tyr323表达纯化得来。

AKR1C2质量控制：＞95%(还原性SDS-PAGE)

AKR1C2制剂：液体

AKR1C2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于AKR1C2：
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).

我公司正在火爆促销分子生物学试剂系列产品，欢迎您的垂询选购重组人高迁移率族蛋白B1(HMGB1)厂家。