北京现货JN1098型重组人Dickkopf相关蛋白2(DK

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括北京现货JN1098型重组人Dickkopf相关蛋白2(DKK-2)优惠在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人Dickkopf相关蛋白2(DKK-2)
品牌：百奥莱博
产地：国产|进口
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp251-Ile526 is expressed with a Fc tag at the N-terminus, 6His tag at the C-terminus.

DKK-2质量控制：＞95%(还原性SDS-PAGE)

DKK-2制剂：冻干品

DKK-2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

DKK-2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于DKK-2：
Dickkopf-related protein 2 (DKK2), is a member of the dickkopf family. DKK2 is secreted protein which contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
关键词：重组人Dickkopf相关蛋白2蛋白,重组Dickkopf相关蛋白2,重组人DKK-2,JN1098


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