特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
JN0900型重组人检查点蛋白(HUS1)厂家现货由专业试剂供应商北京百奥莱博提供,用于生化研究,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人检查点蛋白(HUS1)等分子生物学试剂产品请联系我司咨询订购。
名称:JN0900型重组人检查点蛋白(HUS1)厂家现货
英文名:Recombinant Human Checkpoint Protein HUS1
编号:JN0900
品牌:百奥莱博
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Ser280在N端含有His标签。
HUS1质量控制:>95%(还原性SDS-PAGE)
HUS1制剂:液体
HUS1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于HUS1:
Checkpoint protein HUS1 is a member of the HUS1 family, members of which are shuttled between the nucleus and cytoplasm. HUS1 is expressed in many tissues. HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex involved in arresting the cell cycle in response to DNA damage. DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. HUS1 binds with Rad9 and Rad1 to form the 9-1-1 (RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis and cell cycle arrest.
关于JN0900型重组人检查点蛋白(HUS1)厂家现货的更详细说明,请致电我公司咨询,我们将以最饱满的热情为您提供解答,此外,我公司专业供应下列产品:
·重组小鼠白介素IL-4(C端带His标签)
编号:JN0418
英文名称:Recombinant Mouse Interleukin-4
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的His21-Ser140在C端含有His标签。
IL-4质量控制:>95%(还原性SDS-PAGE)。
IL-4制剂:冻干品
IL-4保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-4复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-4:
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
JN0900型重组人检查点蛋白(HUS1)厂家现货关键词:JN0900,重组人HUS1,重组人检查点蛋白蛋白,重组检查点蛋白
·重组小鼠*结合蛋白S100B
编号:JN1441
英文名称:Recombinant Mouse S100 Calcium Binding Protein B
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Glu92在C端含有His标签。
S100B质量控制:>95%(还原性SDS-PAGE)
S100B制剂:冻干品
S100B保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
S100B复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于S100B:
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytes are the major cells producing S100-B protein in gray matter, as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop, enabling timely delivery of crucial medical intervention before irreversible damage occurs. In addition, S100-B, which is also present in Mouse melanocytes, is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.
JN0900型重组人检查点蛋白(HUS1)厂家现货关键词:JN0900,重组人HUS1,重组人检查点蛋白蛋白,重组检查点蛋白
·重组大鼠IgG2A Fc
编号:JN1538
英文名称:Recombinant Rat Immunoglobulin G2A Fc
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Val98-Lys322表达纯化得来。
IgG2A Fc质量控制:>95%(还原性SDS-PAGE)
IgG2A Fc制剂:冻干品
IgG2A Fc保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IgG2A Fc复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IgG2A Fc:
Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.
我公司生产供应销*(代"售")的分子生物学试剂正全品类优惠促销,十分期待您的咨询选购JN0900型重组人检查点蛋白(HUS1)厂家现货。