特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括北京重组人MECR(线粒体反式烯脂酰-CoA还原酶)厂家在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:北京重组人MECR(线粒体反式烯脂酰-CoA还原酶)厂家
规格:10μg|50μg|500μg|1mg
品牌:百奥莱博
英文名:Recombinant Human Trans-2-Enoyl-CoA Reductase Mitochondrial
编号:JN0763
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Pro54-Met373在C端含有His标签。
MECR质量控制:>95%(还原性SDS-PAGE)
MECR制剂:冻干品
MECR保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
MECR复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于MECR:
Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lower levels in the placenta, liver, kidney and pancreas, with weakly or no expression in the lung. MECR exists as a homodimer, which catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. MECR may take part in the mitochondrial synthesis of fatty acids.
更多有关北京重组人MECR(线粒体反式烯脂酰-CoA还原酶)厂家的价格及使用说明等,请联系我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
·重组小鼠Havcr2(Tim-3)
编号:JN1422
英文名称:Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu22-Ala193在C端含有His标签。
Havcr2/Tim-3质量控制:>95%(还原性SDS-PAGE)
Havcr2/Tim-3制剂:冻干品
Havcr2/Tim-3保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Havcr2/Tim-3复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Havcr2/Tim-3:
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.
北京重组人MECR(线粒体反式烯脂酰-CoA还原酶)厂家关键词:JN0763,重组MECR,重组人MECR,重组人MECR蛋白,重组人线粒体反式烯脂酰-CoA还原酶
·重组人白介素IL-12(白细胞介素12)
编号:JN0399
英文名称:Recombinant Human Interleukin-12
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的Arg23-Ser219&Ile23-Ser328表达纯化而来。
IL-12质量控制:>95%(还原性SDS-PAGE)。
IL-12制剂:冻干品
IL-12保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-12复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-12:
IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.Human and mouse IL‑12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits, respectively. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ. T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.
北京重组人MECR(线粒体反式烯脂酰-CoA还原酶)厂家关键词:JN0763,重组MECR,重组人MECR,重组人MECR蛋白,重组人线粒体反式烯脂酰-CoA还原酶
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