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- 详细信息
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Aldo-Keto Reductase Family 1 Member C2
- 库存:
426
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组人醛酮还原酶家族1成员C2(AKR1C2)厂家直销在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组人醛酮还原酶家族1成员C2(AKR1C2)厂家直销
英文名:Recombinant Human Aldo-Keto Reductase Family 1 Member C2
产地:国产|进口
规格:10μg|50μg|500μg|1mg
编号:JN0698
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Tyr323表达纯化得来。
AKR1C2质量控制:>95%(还原性SDS-PAGE)
AKR1C2制剂:液体
AKR1C2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于AKR1C2:
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
我公司的重组人醛酮还原酶家族1成员C2(AKR1C2)厂家直销,性价比高,货期短,送货上门,欢迎您来电咨询购买,另外,我公司还生产供应销*(代"售")下列产品:
·重组人碳酸酐酶VII(CA7)
编号:JN1917
英文名称:Recombinant Human Carbonic Anhydrase 7
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Ala264在C端含有His标签。
Carbonic Anhydrase VII/CA7质量控制:>95%(还原性SDS-PAGE)
Carbonic Anhydrase VII/CA7制剂:液体
Carbonic Anhydrase VII/CA7保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于Carbonic Anhydrase VII/CA7:
Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore, Alpha-carbonic anhydrase is associated with many biological processes, including calcification, respiration, bone resorption, acid-base balance and the formation of aqueous humor. CA7 is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine, but it is inhibited coumarins, sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet.
重组人醛酮还原酶家族1成员C2(AKR1C2)厂家直销关键词:重组醛酮还原酶家族1成员C2,重组人AKR1C2,重组人醛酮还原酶家族1成员C2,JN0698,重组人醛酮还原酶家族1成员C2蛋白
·重组人TNFα(TNFSF2)
编号:JN0438
英文名称:Recombinant Human Tumor Necrosis Factor alpha
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成。
TNFa/TNFSF2 (high active)质量控制:>95%(还原性SDS-PAGE)
TNFa/TNFSF2 (high active)制剂:冻干品
TNFa/TNFSF2 (high active)保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
TNFa/TNFSF2 (high active)复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于TNFa/TNFSF2 (high active):
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.
重组人醛酮还原酶家族1成员C2(AKR1C2)厂家直销关键词:重组醛酮还原酶家族1成员C2,重组人AKR1C2,重组人醛酮还原酶家族1成员C2,JN0698,重组人醛酮还原酶家族1成员C2蛋白
·重组猕猴SYT1
编号:JN1182
英文名称:Recombinant Macaca mulatta SYT1
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目标蛋白包含序列(Gly98-Lys422) of Macacamulatta SYT1 fused with a polyhistidine tag at the N-terminus.
SYT1质量控制:>95%(SEC-HPLC,还原性SDS-PAGE)
SYT1制剂:冻干品
SYT1保存:
关于SYT1:
Macacamulatta SYT1 is a cytoplasmic vesicle protein which belongs to the synaptotagmin family and contains 2 C2 domains. It may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. SYT1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner: neurexins, syntaxin and AP2.
我公司正在优惠促销分子生物学试剂等系列产品,期待您的咨询选购重组人醛酮还原酶家族1成员C2(AKR1C2)厂家直销。
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