CA9 单克隆抗体

Western Blot（WB）已验证样本:Hela,293T
免疫组织化学（IHC）已验证样本:Human lung cancer
免疫荧光（IF）已验证样本:Human liver cancer

WB 1:1000-1:3000, IHC 1:50-300, IF 1:50-1:200

Monoclonal

IgG

Synthetic Peptide

CA IX

CA-IX;CA9;CAH9;CAIX;Carbonate dehydratase IX;Carbonic anhydrase 9;Carbonic anhydrase IX;Carbonic dehydratase;G250;Membrane antigen MN;MN;P54/58N;pMW1;RCC associated protein G250;RCC-associated antigen G250;Renal cell carcinoma-associated antigen G250抗体

Q16790

50kDa

35-38kDa

Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane. Found on the surface microvilli and in the nucleus, particularly in nucleolus.

Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.

1 mg/mL

在-20℃下储存有效期为12个月。 避免冻融循环。

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Protein A purification

Cancer; Cardiovascular; Metabolism; Signal Transduction

Clone:9B5

Unconjugated

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their sub细胞定位. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.