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文献和实验Chromatin Immunoprecipitation (ChIP)
that the antibody’s ability to recognize its target protein will be compromised by cross-linking. Disadvantages of N-ChIP include the fact that the method is limited to proteins such as histones that associate with DNA with unusually high stability
Abstract ChIP-Chip stands for Ch romatin I mmunop recipitation and chip in the sense of DNA microarray. It is a technique to determine the genome-wide binding sites of a DNA-binding protein. While the basic principle
Whole genome amplification protocol for ChIP-chip
Introduction The technique of chromatin immunoprecipitation (ChIP) has proven to be a powerful tool, allowing the detection of protein-DNA interactions in living cells. Hybridization of ChIP samples to DNA microarrays (i.e. the ChIP
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