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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
InVivoMab anti-human CD25 (IL-2Rα)
- 抗体英文名:
InVivoMab anti-human CD25 (IL-2Rα)
- 靶点:
请见产品说明书
- 浓度:
请见产品说明书
- 应用范围:
Immunoprecipitation, Immunofluorescence
- 宿主:
请见产品说明书
- 适应物种:
human
- 标记物:
无
- 克隆性:
单克隆
- 保存条件:
4度避光
- 形态:
液体
- 亚型:
Mouse IgG2a
- 免疫原:
human CD25 (IL-2Rα)
- 规格:
100 mg
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文献和实验蛋白。正是由于Cdk2和周期素E的活化,T细胞开始分裂并进入细胞周期。据观察,激活的T细胞ld可以分裂2-3次,产生大量子代细胞。 显然,T细胞没有进入激活状态,就不会有各种基因的表达,包括IL2和IL2Ra编码基因,因而也无法启动由细胞因子IL2受体介导的信号转导。换言之,细胞因子IL-2一般不会作用于未致敏和未被激活的CD4 T细胞,因为这些细胞表面不能有效地构成由α、β、γ三链组成的高亲和力ID2受体。 另外需要指出的是,IL2R。又称CD25
Polyclonal Expansion of Human CD4+CD25+ Regulatory T Cells
for the efficient in vitro expansion of human Treg cells and identified CD4+ CD25high CD45RA+ T cells as the ideal starting population for the generation of homogeneous and stable Treg cell products. Here, we provide detailed instructions for their identification
Human CD4+CD25highCD127low/neg Regulatory T Cells
.g., IL-2. Expanded Tregs retain their suppression function. Human Tregs have demonstrated their great potential to be used as a therapeutic intervention in preventing graft rejection and treating autoimmune diseases. In this chapter, we have given
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