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MOUSE ANTI PIG CD46

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  • 询价
  • BIO-RAD已认证
  • MCA2262GA
  • UK
  • 2025年11月12日
  • F
  • Mouse
  • Pig
  • 详细信息
  • 文献和实验
  • 技术资料
  • 抗体名

    CD46 antibody | JM6C11

  • 抗体英文名

    MOUSE ANTI PIG CD46

  • 浓度

    IgG concentration 1.0 mg/ml

  • 应用范围

    F

  • 宿主

    Mouse

  • 适应物种

    Pig

  • 保质期

    自发货之日起 12 个月

  • 目录编号

    JM6C11

  • 供应商

    伯乐生命医学产品(上海)有限公司

  • 标记物

    Purified

  • 克隆性

    Monoclonal Antibody

  • 形态

    Purified IgG - liquid

  • 亚型

    IgG1

  • 免疫原

    Porcine peripheral blood mononuclear cells

  • 规格

    0.1 mg

Mouse anti Pig CD46 antibody, clone JM6C11 recognizes porcine CD46, also known as membrane cofactor protein (MCP). CD46 is a ~45-65 kDa single pass type 1 transmembrane glycoprotein expressed by all peripheral blood cells.

Mouse anti Pig CD46 antibody, clone JM6C11 inhibits functional MCP cofactor activity as measured by inhibition of cleavage of the α chain of C3 (Pérez De La Lastra et al. 1999).


储存信息

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.


应用

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry 1/10
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10μl of the suggested working dilution to label 106 cells in 100μl


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图标文献和实验
该产品被引用文献

References for CD46 antibody

  1. van den Berg, C.W. et al. (1997) Purification and characterization of the pig analogue of human membrane cofactor protein (CD46/MCP).
    J Immunol. 158: 1703-9.
  2. Haverson, K. et al. (2001) Overview of the Third International Workshop on Swine Leukocyte Differentiation Antigens.
    Vet Immunol Immunopathol. 80: 5-23.
  3. Pérez De La Lastra, J.M. et al. (1999) Epitope mapping of 10 monoclonal antibodies against the pig analogue of human membrane cofactor protein (MCP).
    Immunology. 96: 663-70.
  4. Dräger, C. et al. (2015) Porcine complement regulatory protein CD46 and heparan sulfates are the major factors for classical swine fever virus attachment in vitro.
    Arch Virol. 160: 739-46.

Further Reading

  1. Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
    Vet Res. 39: 54.
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MOUSE ANTI PIG CD46
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