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  • ¥350
  • YOYOBIO
  • 上海
  • YJ-B21678-20mg
  • 2026年01月16日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      -20℃

    • 保质期

      见包装

    • 英文名

      Catalpol

    • 库存

      大量现货

    • 供应商

      上海研谨生物

    • CAS号

      2415-24-9

    • 规格

      20mg

    梓醇

    分析标准品,HPLC≥98%

    Catalpol

    CAS号:2415-24-9

    分子式:C15H22O10

    分子量:362.333

    MDLMFCD11111524

    货号

    规格/参数/品牌

    价格

    货期

    YJ-B21678-20mg

    分析标准品,HPLC≥98%

    350.00

    现货

    YJ-B21678-100mg

    分析标准品,HPLC≥98%

    840.00

    现货

    A10108-20mg

    分析标准品,含量99.6%,可溯源

    460.00

    现货

    JT92409-1ml51

    10mM in DMSO

    814.00

    现货

     

    产品介绍

    药理药效:有抗癌、神经保护、抗炎、利尿、降血糖及抗肝炎病毒等作用。

    熔点:203-205℃

    沸点:675.6 ℃ at 760 mmHg

    比旋光度:-122 (EtOH aq.)

    外观:白色粉末

    溶解性:水:5mg/ml

    储存条件:-20℃

    注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

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    图标文献和实验
    该产品被引用文献

    参考文献(50)

    50. [IF=4.8] Shu-jie Yu et al."Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking approaches."Frontiers in Plant Science.2025 Jul;16:

    49. [IF=1.7] Liu Zibin et al."Catalpol inhibits Hedgehog signaling pathway to suppress proliferation and promote lipid accumulation in rat meibomian gland epithelial cells."CYTOTECHNOLOGY.2025 Jun;77(3):1-16

    48. [IF=3.3] Xue Chen et al."Role of IGF1/IGFR signaling pathway in neuroprotective effect of Shengmai Dihuang Decoction on CIH-induced cognitive impairment."Journal of Traditional and Complementary Medicine.2024 Nov;:

    47. [IF=2.8] Shuo Wang et al."Screening of ESR2-targeted anti-postmenopausal osteoporosis chemistry from Rehmanniae Radix Preparata based on affinity ultrafiltration with UPLC-QE-Orbitrap-MS."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LI

    46. [IF=4.4] Zishan Huang et al."Catalpol promotes hippocampal neurogenesis and synaptogenesis in rats after multiple cerebral infarctions by mitochondrial regulation: involvement of the Shh signaling pathway."Frontiers in Pharmacology.2024 Dec;15:

    45. [IF=4.7] Zhengyao Yu et al."Exploring the Therapeutic and Gut Microbiota-Modulating Effects of Qingreliangxuefang on IMQ-Induced Psoriasis."Drug Design Development and Therapy.

    44. [IF=5.3] Jingjing Yang et al."Exploration on the mechanism of “black as lacquer and sweetness as candy” based on the reactions of “crosslinking coloring and Maillard” and “oligosaccharide hydrolysis” during the processing of Radix Rehmanniae."Arabian Journal of Ch

    43. [IF=6.7] Xin Ye Ji et al."Catalpol alleviates heat stroke-induced liver injury in mice by downregulating the JAK/STAT signaling pathway."PHYTOMEDICINE.2024 Sep;132:155853

    42. [IF=5.3] Yuyi Wu et al."A gel plaster in the form of nipple cover: A comfortable and safe transdermal delivery method for mammary hyperplasia."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2024 Sep;662:124500

    41. [IF=4.6] Jingjing Yang et al."Exploration of the Dynamic Variations of the Characteristic Constituents and the Degradation Products of Catalpol during the Process of Radix Rehmanniae."MOLECULES".2024 Jan;29(3):705

    40. [IF=3.5] Yuanjun Li et al."Transcriptome Analysis Provides Insights into Catalpol Biosynthesis in the Medicinal Plant Rehmannia glutinosa and the Functional Characterization of RgGES Genes."Genes.2024 Feb;15(2):155

    39. [IF=7.9] Shuai Chen et al."Catalpol attenuates osteoporosis in ovariectomized rats through promoting osteoclast apoptosis via the Sirt6-ERα-FasL axis."PHYTOMEDICINE.2024 Jan;123:155262

    38. [IF=3.9] Ying Zhang et al."Potential benefits of Rehmanniae Radix after ancient rice-steaming process in promotion of antioxidant activity in rats' health."Food Science & Nutrition.2023 Jun;:

    37. [IF=7.5] Si Li et al."Catalpol rescues cognitive deficits by attenuating amyloid β plaques and neuroinflammation."BIOMEDICINE & PHARMACOTHERAPY.2023 Sep;165:115026

    36. [IF=2.65] Minghui Wu et al."Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice."Evidence-based Complementary and Alternative Medicine.2022 Nov 25;2022:7074157

    35. [IF=3.978] Du Jikun et al."Catalpol Ameliorates Neurotoxicity in N2a/APP695swe Cells and APP/PS1 Transgenic Mice."NEUROTOXICITY RESEARCH.2022 Jun;:1-12

    34. [IF=2.759] Yuxi Di et al."Catalpol Inhibits Tregs-to-Th17 Cell Transdifferentiation by Up-Regulating Let-7g-5p to Reduce STAT3 Protein Levels."Yonsei Med J. 2022 Jan; 63(1): 56–65

    33. [IF=1.982] Lili Song et al."Metabolism of Du Zhong Formula in rats using UPLC-Q-TOF/MS."J Mass Spectrom. 2022 Jan;57(1):e4795

    32. [IF=2.984] Linluo Zhang et al."Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway."Peerj. 2022 Jan;10:e12759

    31. [IF=3.935] Yong-Sheng Wu et al."Chemical profiling of Callicarpa nudiflora and its effective compounds identification by compound-target network analysis."J Pharmaceut Biomed. 2020 Apr;182:113110

    30. [IF=4.162] Weixin Hou et al."The Jieduan-Niwan (JDNW) Formula Ameliorates Hepatocyte Apoptosis: A Study of the Inhibition of E2F1-Mediated Apoptosis Signaling Pathways in Acute-on-Chronic Liver Failure (ACLF) Using Rats."Drug Des Dev Ther. 2021; 15: 3845–3862

    29. [IF=4.183] Wan Gong et al."Rehmannia glutinosa Libosch Extracts Prevent Bone Loss and Architectural Deterioration and Enhance Osteoblastic Bone Formation by Regulating the IGF-1/PI3K/mTOR Pathway in Streptozotocin-Induced Diabetic Rats."Int J Mol Sci. 2019 Jan;20(16

    28. [IF=4.225] Yang  Fan et al."Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways."Front Pharmacol. 2021 Jan;11:2472

    27. [IF=4.225] Yang  Chunjing et al."Neuroprotective Effect of Catalpol via Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Mechanisms."Front Pharmacol. 2020 May;11:690

    26. [IF=4.36] Chenglin Song et al."Deciphering the mechanism of Fang-Ji-Di-Huang-Decoction in ameliorating psoriasis-like skin inflammation via the inhibition of IL-23/Th17 cell axis."J Ethnopharmacol. 2021 Dec;281:114571

    25. [IF=6.6] Longtai You et al."Catalpol Protects ARPE-19 Cells against Oxidative Stress via Activation of the Keap1/Nrf2/ARE Pathway."Cells-Basel. 2021 Oct;10(10):2635

    24. [IF=2.1] Yun  Han et al."Antiangiogenic effects of catalpol on rat corneal neovascularization."Mol Med Rep. 2018 Feb;17(2):2187-2194

    23. [IF=2.479] Yang  Tao et al."Effect of catalpol on remyelination through experimental autoimmune encephalomyelitis acting to promote Olig1 and Olig2 expressions in mice."Bmc Complem Altern M. 2017 Dec;17(1):1-15

    22. [IF=4.411] Dan-Dan Tian et al."Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats."Molecules. 2016 Jun;21(6):696

    21. [IF=4.411] Wei Wang et al."In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism."Molecules. 2016 May;21(5):597

    20. [IF=4.545] Chao Lin et al."Catalpol protects glucose-deprived rat embryonic cardiac cells by inducing mitophagy and modulating estrogen receptor."Biomed Pharmacother. 2017 May;89:973

    19. [IF=4.759] Mingzhen He et al."Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv."J C

    18. [IF=6.799] Yun Tang et al."Quantifying orientational regeneration of injured neurons by natural product concentration gradients in a 3D microfluidic device."Lab Chip. 2018 Mar;18(6):971-978

    17.  Wang, Wei, Dan-Dan Tian, and Zhang-Jin Zhang. "In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism." Molecules 21.5 (2016): 597.https:##doi.org/10.3390/molecules21050597

    16.  He, Mingzhen, et al. "Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv."

    15.  Lin, Chao, et al. "Catalpol protects glucose-deprived rat embryonic cardiac cells by inducing mitophagy and modulating estrogen receptor." Biomedicine & Pharmacotherapy 89 (2017): 973-982.https:##doi.org/10.1016/j.biopha.2017.02.069

    14.  Yang, Tao, et al. "Effect of catalpol on remyelination through experimental autoimmune encephalomyelitis acting to promote Olig1 and Olig2 expressions in mice." BMC complementary and alternative medicine 17.1 (2017): 1-15.https:##doi.org/10.1186/s12906-017

    13.  Yang, Chunjing, et al. "Neuroprotective effect of catalpol via anti-oxidative, anti-inflammatory, and anti-apoptotic mechanisms." Frontiers in Pharmacology 11 (2020): 690.https:##doi.org/10.3389/fphar.2020.00690

    12.  化宝军,赵世莉,苏妍妍,杨椹.梓醇对急性肾损伤大鼠TLR4/NF-κB通路及肾小球内皮损伤的影响[J].中国中西医结合肾病杂志,2020,21(12):1042-1046+1137.

    11.  李尽文,宋代博,李苑华,麦键城,刘咏倩,李莉.梓醇对宫颈癌HeLa细胞增殖及凋亡作用的研究[J].山东化工,2020,49(17):43-45.

    10.  陶玉菡,许惠琴,李莉,农伟虎,李伟.生地、山茱萸抑制和清除糖基化产物的效应成分研究[J].中药药理与临床,2013,29(04):30-33.

    9.  周炳文, 钟晓明, 黄真. 玄参环烯醚萜苷热回流提取工艺的优化[J]. 中成药, 2018, 040(006):1292-1297.

    8.  蒙雄裕, 徐良, 李华强,. RP-HPLC法测定天目地黄中梓醇和毛蕊花糖苷的含量[J]. 药学服务与研究, 2015, 15(004):273-276.

    7.  陆春红, 许惠琴, 刘凯,. 生地环烯醚萜苷类成分对AGEs损伤HUVEC的保护作用[J]. 南京中医药大学学报, 2015, 31(001):55-59.

    6.  李强, 胡晶红, 张永清,. 晒干与烘干生地黄产量和质量比较[J]. 山东中医杂志, 2013(09):58-59+77.

    5.  王素云, 卢颖, 蔡丹凤,. 基于雌激素受体探讨梓醇对抗糖剥夺心肌细胞损伤的作用[J]. 中国药理学通报, 2019.

    4.  和大奎, 朱文学, 于斌,. 地黄浸膏超声真空干燥特性和动力学研究[J]. 江苏农业科学, 2017, 45(013):157-164.

    3.  李民,辛杰,王春艳,李民,张淹.地黄中梓醇含量与产区相关性研究[J].中国药物评价,2014,31(04):212-214.

    2.  张路  王春艳  李士栋 等. 响应面设计优化地黄中梓醇的提取工艺研究[J]. 中国药物评价  2015  000(001):12-16.

    1.  周霞 张文倩 刘炬 李丽 刘付红 刘炳男.从血管内皮生长因子及其受体调控角度探讨地黄梓醇促血管新生作用及分子机制研究[J].实用心脑肺血管病杂志 2020 28(02):64-68.

    相关实验
    • 玄参科

      ;蒴果卵形。根状茎为传统中药,有清热生津、凉血止血、润燥、滋阴补肾、补血调经之效。含梓醇(catalpol)、地黄素(reh-mannia)、水苏糖(stachose)等多种糖及赖氨酸等多种氨基酸。   毛地黄 又称洋地黄,原产欧洲,中国有栽培。多年生直立草本,除花冠外全体被灰色柔毛和腺毛;基生叶莲座状,叶片长卵形;总状花序顶生,花朝向一边,花萼5深裂;花冠近2唇形,筒长,裂片短,紫红色,内面具斑点;雄蕊2强;蒴果卵形。叶供药用,有强心之效,现制成各种强心剂。含强心苷类。(参见彩图插页

    • RPHPLC法测定熟地黄中五羟甲基糠醛(5HMF)含量的方法

      glutinosa Libosch的根,经加工炮制而成. 熟地黄在临床上应用较为广泛[1]. 熟地黄含有梓醇、糖类、甙类、5羟甲基糠醛(5HMF)等化学成分,其中5HMF是熟地黄质量控制的量化指标之一[2]. 文献报道生地黄炮制成熟地黄后5HMF的含量增加20倍左右[3]. 而5HMF对人体横纹肌及内脏有损害[4];具有神经毒性,能与人体蛋白质结合产生积蓄中毒[5]. 熟地黄中5HMF含量测定报道较少,如薄层扫描法(TLCS)[3,6]. 但TLCS法操作复杂、受试条件重复性差. 我们采用RPHPLC法测定

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