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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
见包装
- 英文名:
Protopanaxdiol
- 库存:
大量现货
- 供应商:
上海研谨生物
- CAS号:
30636-90-9
- 规格:
20mg
原人参二醇
分析标准品,HPLC≥98%
Protopanaxdiol
CAS号:30636-90-9
分子式:C30H52O3
分子量:460.739
MDL:MFCD12032048
别名:人参皂苷APPD;20-Epiprotopanaxadiol; 20(S)-APPD;20(S)-原人参二醇; 原人参二醇(PPD);;Protopanaxtriol; PROTOPANAXDIOL; (20S)-Protopanaxadiol; 20(S)-Protopanaxdiol
|
货号 |
规格/参数/品牌 |
价格 |
货期 |
|
YJ-B21619-20mg |
分析标准品,HPLC≥98% |
¥470.00 |
现货 |
|
YJ-B21619-200mg |
分析标准品,HPLC≥98% |
¥2380.00 |
现货 |
|
JT91408-1ml买5赠1 |
10mM in DMSO |
¥431.00 |
现货 |
产品介绍
熔点:236-238℃
沸点:559.5℃ at 760mmHg
比旋光度:+20.5 (CHCl3)
外观:白色晶体
溶解性:可溶于丙tong、DMSO等溶剂。
储存条件:2-8℃
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文献和实验参考文献(32篇)
32. [IF=3.8] Qin Wei et al."Target Identification of Ginsenosides Against Cognitive Impairment by Using Mass Spectrometry-Based Cellular Thermal Shift Assay (CETSA)."NEUROCHEMICAL RESEARCH.2025 Jun;50(3):1-17
31. [IF=4.2] Pengli Guo et al."20 (S)-Protopanaxadiol Alleviates DRP1-Mediated Mitochondrial Dysfunction in a Depressive Model In Vitro and In Vivo via the SIRT1/PGC-1α Signaling Pathway."MOLECULES.2024 Jan;29(21):5085
30. [IF=11.4] Keqin Lu et al."Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NET formation."Journal of Advanced Resear
29. [IF=3.1] Ze-xuan Chen et al."Metabolite profiling of Shenhua compound in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL
28. [IF=3.8] Saiya Chen et al."Molecular network strategies combined with MCnebula2 identify potential active compounds from steamed Polygonatum cyrtonema Hua."JOURNAL OF CHROMATOGRAPHY A.2025 Feb;:465779
27. [IF=6.8] Ye Zhang et al."The Antitumor Effects and Apoptotic Mechanism of 20(S)-Protopanaxadiol in Acute Myeloid Leukemia."Journal of Ginseng Research.2025 Mar;:
26. [IF=6.8] Feiyan Chen et al."Identification of AIF1 as a protein target of notoginsenosides in brain tissue of mice with intracerebral hemorrhage based on hapten immunoaffinity fishing technique."Journal of Ginseng Research.2025 Apr;:
25. [IF=3.8] Chen Yue et al."Impact of ginsenoside Rb1 on gut microbiome and associated changes in pharmacokinetics in rats."Scientific Reports.2024 Sep;14(1):1-12
24. [IF=2.7] Wenjie Su et al."Therapeutic effect of notoginseng saponins before and after fermentation on blood deficiency rats."Experimental and Therapeutic Medicine".2024 Apr;27(4):1-16
23. [IF=4.6] Zhongyi Cong et al."Transcriptome Analysis of the Inhibitory Effects of 20(S)-Protopanaxadiol on NCI-H1299 Non-Small Cell Lung Cancer Cells."MOLECULES.2023 Jan;28(15):5746
22. [IF=7.2] Jinfen Chen et al."20(S)- Protopanaxadiol saponins isolated from Panax notoginseng target the binding of HMGB1 to TLR4 against inflammation in experimental ulcerative colitis."PHYTOTHERAPY RESEARCH.2023 Jul;:
21. [IF=6.1] Yue-guang Mi et al."Comparative Characterization of the Ginsenosides from Six Panax Herbal Extracts and Their In Vitro Rat Gut Microbial Metabolites by Advanced Liquid Chromatography–Mass Spectrometry Approaches."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
20. [IF=5.735] Feiyan Chen et al."Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction."Journal of Ginseng Research.2023 Apr;:
19. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199
18. [IF=6.055] Baoyu Fu et al."Ginsenosides improve reproductive capability of aged female Drosophila through mechanism dependent on ecdysteroid receptor (ECR) and steroid signaling pathway."Frontiers in Endocrinology.2022; 13: 964069
17. [IF=10.269] Zhang Xuefei et al."A multifunctional cholesterol-free liposomal platform based on protopanaxadiol for alopecia therapy."Nano Research.2022 Jul;:1-13
16. [IF=5.396] Ye-Wei Huang et al."20(S)-protopanaxadiol decreases atherosclerosis in the ApoE KO mice by increasing the levels of LDLR and inhibiting its binding with PCSK9."Food & Function. 2022 May;:
15. [IF=6.06] Zhu Zhu et al."Target engagement of ginsenosides in mild cognitive impairment using mass spectrometry-based drug affinity responsive target stability."J Ginseng Res. 2021 Dec;:
14. [IF=5.753] Jianghong Gao et al."Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum.."Front Plant Sci. 2021 Dec;12:809579-809579
13. [IF=2.547] Zhongyi Cong et al."Ginsenoside Rh3 Inhibits Proliferation and Induces Apoptosis of Colorectal Cancer Cells."Pharmacology. 2020;105(5-6):329-338
12. [IF=2.629] Zhang Meiyu et al."In Vitro Transformation of Protopanaxadiol Saponins in Human Intestinal Flora and Its Effect on Intestinal Flora."Evid-Based Compl Alt. 2021;2021:1735803
11. [IF=3.645] Hao Zhang et al."Preparing molecularly imprinted nanoparticles of saponins via cooperative imprinting strategy."J Sep Sci. 2020 Jun;43(11):2162-2171
10. [IF=4.24] Yuan Liang et al."Multi-spectroscopic and molecular modeling studies on the interactions of serum albumin with 20(S, R)-protopanaxadiol and 20(S, R)-protopanaxatriol that inhibit HCT-116 cells proliferation."Food Biosci. 2021 Apr;40:100913
9. [IF=4.679] Tiehua Zhang et al."20(S)-Protopanaxadiol blocks cell cycle progression by targeting epidermal growth factor receptor."Food Chem Toxicol. 2020 Jan;135:111017
8. [IF=5.279] Yanan Gao et al."Galactosylation of Monosaccharide Derivatives of Glycyrrhetinic Acid by UDP-Glycosyltransferase GmSGT2 from Glycine max."J Agr Food Chem. 2020;68(32):8580–8588
7. [IF=5.396] Hui Wang et al."Ginsenoside extract from ginseng extends lifespan and health span in Caenorhabditis elegans."Food Funct. 2021 Aug;12(15):6793-6808
6. [IF=5.81] Zhang He et al."Platelet Protease Activated Receptor 1 Is Involved in the Hemostatic Effect of 20(S)-Protopanaxadiol by Regulating Calcium Signaling."Front Pharmacol. 2020 Sep;0:1483
5. [IF=6.023] Tiehua Zhang et al."Identification of 20(R, S)-protopanaxadiol and 20(R, S)-protopanaxatriol for potential selective modulation of glucocorticoid receptor."Food Chem Toxicol. 2019 Sep;131:110642
4. [IF=6.06] Zhenzhuo Li et al."Ginsenosides repair UVB-induced skin barrier damage in BALB/c hairless mice and HaCaT keratinocytes."J Ginseng Res. 2021 May;:
3. [IF=6.06] Jiahong Han et al."Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis."J Ginseng Res. 2020 Mar;44:291
2. Zhang H, Pan D, Wu X, Su W, Tang X, Zhao D, Sun L, Song B, Bai X, Li X. Platelet Protease Activated Receptor 1 Is Involved in the Hemostatic Effect of 20(S)-Protopanaxadiol by Regulating Calcium Signaling. Front Pharmacol. 2020 Sep 18;11:549150. doi: 10.33
1. 宿文杰,张玉尧,李荣森,王隶书,徐云凤,张鹤.20(S)-原人参二醇止血作用及其机制[J].中成药,2021,43(03):605-612
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